For patients with severe coronary artery disease, heart bypass surgery can reduce the risk of heart attack and improve overall quality of life. Now, researchers report the possibility of a new treatment that may be even more beneficial, without the surgery.. Researchers say the protein AGGF1 could be a promising treatment for coronary heart disease and heart attack. Coronary artery disease (CAD) is the most common form of heart disease in the United States, responsible for more than 370,000 deaths in the country every year.The condition arises when plaque builds up in the coronary arteries, partially or fully blocking the flow of oxygen-rich blood to the heart muscle. This blockage can cause heart attack, angina – severe chest pain – and, over time, heart failure. While lifestyle changes – such as adopting a healthy diet and regular physical activity – are considered key to improving CAD, some patients may require heart bypass surgery, which can help restore blood flow to the heart. But, as with all surgery, it has its risks. These include chest wound infection, bleeding, stroke, heart attack, and kidney or lung failure.