Cancer drug may help increase the number of new eggs in women: Study
A new study has revealed that a treatment with cancer drug may help increase the number of young eggs in women’s ovaries. Researchers believed that more research is needed to better understand the implications, though it is too soon to link the outcome to fertility.
The study was published in the journal Human Reproduction. If further research can reveal the mechanism by which treatment with the drug combination, known as ABVD, results in increased production of eggs, this would aid understanding of how women might be able to produce more eggs during their lifetime. This was until recently thought to be impossible. Lead researcher Evelyn Telfer, Professor at University of Edinburgh in Britain, said “This study involves only a few patients, but its findings were consistent and its outcome may be significant and far-reaching. We need to know more about how this drug combination acts on the ovaries and the implications of this”. Researchers have analysed samples of ovary tissue donated by 14 women who had undergone chemotherapy, and from 12 healthy women. The findings showed that the ovaries from eight of the cancer patients, who had been treated with a drug combination, had a much greater incidence of immature, or non-growing, eggs compared with tissue from women who had received a different chemotherapy, or from healthy women of a similar age. The ovary tissue was seen to be in healthy condition, appearing similar to tissue from young women’s ovaries. Researchers had set out to better understand why treatment with ABVD is one of the few cancer drug combinations that do not impact women’s fertility.