Four women have had new vaginas grown in the laboratory and implanted by doctors in the US.
A tissue sample and a biodegradable scaffold were used to grow vaginas in the right size and shape for each woman as well as being a tissue match.
They all reported normal levels of “desire, arousal, lubrication, orgasm, satisfaction” and painless intercourse. Experts said the study, published in the Lancet, was the latest example of the power of regenerative medicine.
In each woman the vagina did not form properly while they were still inside their mother’s womb, a condition known as vaginal aplasia.
Current treatments can involve surgically creating a cavity, which is then lined with skin grafts or parts of the intestine.
Doctors at Wake Forest Baptist Medical Centre in North Carolina used pioneering technology to build vaginas for the four women who were all in their teenage years at the time.
Scans of the pelvic region were used to design a tube like 3D-scaffold for each patient.
A small tissue biopsy was taken from the poorly developed vulva and grown to create a large batch of cells in the laboratory.