With in-vitro fertilization gaining popularity as a means to conceive a baby, more and more couples are resorting to the procedure. Of course, the process doesn’t guarantee conception on the first try – a disappointment which often tempts the couple to go for another round in desperation. However, a new study has found that a failed fertilization therapy increases a woman’s risk of developing long-term cardiovascular disease, compared to women who become pregnant through the process. The reason for this are the drugs that are used for the fertility treatment, which reserchers believe could impact the blood pressure levels as well as increase the risk of blood clots. “We found that two-thirds of women never became pregnant after being managed for fertility treatment and these women also had worse long-term cardiovascular risk, specifically higher risks of stroke and heart failure, compared to the remaining third of women who did become pregnant and delivered a baby,” said lead author Jacob Udell, cardiologist at the Women’s College Hospital in Ontario, Canada. The findings showed that fertility therapy failure was associated with a 19 percent increased risk of adverse cardiovascular events, in particular, heart failure. Only about ten in 1,000 suffered heart problems after failed fertility therapy, compared to six in 1,000 for those who had successful treatment, the researchers stressed. “These findings are consistent with the hypothesis that fertility therapy may represent an early indication for future cardiovascular disease because it represents a unique cardiometabolic stress test,” Udell said. For the study, published in the Canadian Medical Association Journal, the team looked at data on 28,442 women under age 50 who underwent fertility therapy in Ontario. However, the results should be interpreted with caution, the researchers suggested.