A multiple sclerosis treatment being tested in patients can stop the disease for at least five years, say doctors. The risky therapy involves wiping out the person’s immune system with strong cancer drugs and then rebooting it with a stem cell transplant. Doctors say only a few patients can try it, due to the high risk. Out of 281 people who had the treatment, nearly half benefited, but eight died shortly afterwards.  The work in JAMA Neurology is one of the largest and longest investigations of this aggressive MS treatment. “It was a hard decision, knowing what could go wrong. My wife and I discussed it for many, many hours. We’ve got small children and I didn’t want my MS to get worse and end up in a wheelchair.  “I did this to halt the condition and so that I can be there for my children, who are still so young. I want to be able to play rugby and football with them as they grow up.” What is not clear is for how long the therapy might ultimately work.

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