New Delhi: Tobacco harms nearly every organ in the body, including the heart, blood vessels, lungs, eyes, mouth, reproductive organs, bones, bladder, and digestive organs. According to the World Health Organisation (WHO), tobacco uses kill nearly six million people in a year, of which around five million of those deaths are the result of direct tobacco use. While more than 600,000 is the result of non-smokers being exposed to second-hand smoke. The scenario is equally scary in India with estimated number of tobacco users being 274.9 million. As per Global Adult Tobacco Survey India (GATS), about 163.7 million Indians use smokeless tobacco, whereas 68.9 million people are smokers. Also 42.3 millions are users of both smoking and smokeless tobacco. It means around 35% of adults (47.9% males and 20.3% females) in India use tobacco in some form or the other. Tobacco products contain around 5000 toxic substances, however, the most important and dangerous constituents are – nicotine, carbon monoxide and tar. Nicotine, a poisonous substance leads to addiction, is more addictive and deadlier than cocaine. Nicotine travels rapidly to the brain, in a matter of seconds, after absorption. The side effects of nicotine can affect the heart, hormones and the gastrointestinal system.